Mouse secreted CD137, also known asTumor Necrosis Factor ReceptorSuperfamily member 9, TNFRSF9, and ILA,GenBank Accession No. NM_011612, a.a.24-187 fused at the C-terminus to the Fcportion of human IgG1, expressed in aHEK293 cell expression system. MW = 44kDa (monomer). This protein runs at ahigher MW by SDS-PAGE due toglycosylation.
Immunogen Region
24-187
Tag
Fc fusion (hIgG1)
Formulation
8 mM Na Phosphate pH 7.4, 110 mM NaCl, 2.2 mM KCl and 20% glycerol.
Species
mouse
Application
Useful for studying protein binding and screening small molecular inhibitors
Notes
The aggregation state of this product has been confirmed to be<10%. Avoidfreeze/thaw cycles. Storing diluted protein isnot recommended, if necessary, includecarrier protein (BSA 0.1 - 0.5%).
GenBank
NM_011612
Mw(kda)
44 kDa
Synonyms
Tumor Necrosis Factor Receptor Superfamily member 9, TNFRSF9, and ILA
Uniprot
P20334
Shipping Temperature
-80°C (dry ice)
Format
Aqueous buffer solution
Storage
At least 6 months at -80°C.
Reference
1. Wilcox, R.A., et al., J. Clin. Invest. 2002; 109(5): 651-659. 2. Foell, J. et al., J. Clin. Invest. 2003; 111(10): 1505-1518.