Mouse B7-2 Protein, hFc Tag

Mfr.No.	PME-M100046
Description	Recombinant mouse B7-2 protein with C-terminal human Fc tag
Background	This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is eXpressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoXic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for actIVation of the T-cell. Binding of this protein with cytotoXic T-lymphocyte-associated protein 4 negatIVely regulates T-cell actIVation and diminishes the immune response. AlternatIVe splicing results in several transcript variants encoding different isoforms.
Tag	C-Human Fc tag
Formulation	Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Molecular Weight	The protein has a predicted molecular mass of 51.4 kDa after removal of the signal peptide. The apparent molecular mass of mB7-2-hFc is approXimately 55-70 kDa due to glycosylation.
Host	HEK293
Notes	Research use only

Purity	The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
Storage	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

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SKU	Supplier No.	Size	Your price
BHP18100671	PME-M100046	100 ug	$568	Add to Cart
BHP18100671	PME-M100046	50 ug	$388	Add to Cart
BHP18100671	PME-M100046	10 ug	$103	Add to Cart