Monkey secreted Programmed Cell Death 1 (PD-1)-Fc fusion protein, also known as CD279, PDCD1, and SLEB2, GenBank Accession No. NM_005018, a.a. 25-167, fused at the C-terminus to the Fc portion of human IgG1, expressed in a HEK293 cell expression system. MW = 42.6 kDa. Note: this protein runs at an apparent higher molecular weight due to glycosylation.
Immunogen Region
25-167
Tag
C-terminal Fc fusion (Human IgG1)
Formulation
8 mM phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, pH 7.4, and 20% glycerol
Species
Macaca fascicularis
Application
Useful for the study of protein-protein interaction and in vitro and in vivo protein function studies.
Notes
This protein runs at an apparent highermolecular weight due to glycosylation. The aggregation state of this product has been confirmed to be<10%. Avoid freeze/thaw cycles. Protein may be diluted to>=100 ug/ml in PBS + glycerol and stored at -80°C.
GenBank
NM_001284136.1
Mw(kda)
42.6 kDa
Synonyms
Programmed cell death 1, PDCD1, PD-1, PD1, SLEB2, CD279, HPD-L
Shipping Temperature
-80°C (dry ice)
Format
Aqueous buffer solution
Storage
At least 6 months at -80°C.
Reference
1. Shinohara, T., et al., Genomics. 1994Oct;23(3):704-6. 2. James, E.S., et al., Genes Immun. 2005Aug;6(5):430-7.