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Home / Proteins & Peptide

MIP-3alpha/CCL20, Mouse

SKU : BHP18500168

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iXCells Biotechnologies

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Mfr.No.	IX02955, IX02955-1, IX02955-20, IX02955-5
Description	MIP-3alpha/CCL20, also known as LARC (Liver and Activation-regulated Chemokine) and as Exodus, is a CC chemokine that is expressed in the liver, lymph nodes, appendix, PBL and lung and can signal through the CCR6 receptor. MIP-3 alpha is chemotactic towards lymphocytes and dendritic cells. Additionally, it promotes the adhesion of memory CD4+ T cells and inhibits colony formation of bone marrow myeloid immature progenitors.
Reconstitution	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at <= -20 °C. Further dilutions should be made in appropriate buffered solutions.
Formulation	Lyophilized from a 0.2 um filtered concentrated solution in PBS, pH 7.4.
Molecular Weight	Approximately 8.0 kDa, a single non-glycosylated polypeptide chain containing 70 amino acids.
Physical Appearance	Sterile Filtered White lyophilized (freeze-dried) powder.
Source	E. coli
Host	Mouse
Endotoxin Level	Less than 1 EU/ug of rMuMIP-3alpha/CCL20 as determined by LAL method.
Bioactivity	Fully biologically active when compared to standard. The biologically active determined by a chemotaxis bioassay using human CCR6 transfected murine BaF3 cells is in a concentration range of 0.1-10 ng/ml.

Synonyms	Macrophage Inflammatory Protein-3?, CCL20, LARC, Exodus-1
Sequence	ASNYDCCLSY IQTPLPSRAI VGFTRQMADE ACDINAIIFHTKKRKSVCAD PKQNWVKRAV?NLLSLRVKKM

Purity	96 % by SDS-PAGE and HPLC analyses.
Storage	This lyophilized preparation is stable at 2-8 °C, but should be kept at -20 °C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 °C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 °C to -70 °C. Avoid repeated freeze/thaw cycles.

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHP18500168-1	IX02955-1	1mg	$2621		Add to Cart
BHP18500168-2	IX02955-20	20ug	$199		Add to Cart
BHP18500168-3	IX02955-5	5ug	$82		Add to Cart

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