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Home / Proteins & Peptide

MIG/CXCL9, Mouse

SKU : BHP18500476

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iXCells Biotechnologies

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Mfr.No.	IX03343, IX03343-1, IX03343-25, IX03343-5
Description	Chemokine (C-X-C motif) ligand 9 (CXCL9), also known as monokine induced by interferon gamma (MIG), is a small cytokine belonging to the CXC chemokine family.The CXCL9 gene is induced in macrophages and in primary glialcells of the central nervous systemin response to IFNgamma. CXCL9 has been shown to be achemo attractant for activated Th1lymphocytes and tumor-infiltrating leukocytes (TILs) but not for neutrophils or monocytes. CXCL is also involved in other cellular activities including inhibition of tumor growth, angiogenesis, and inhibition of colony formation of hematopoietic progenitors.CXCL9 is closely related to two other CXC chemokines, CXCL10 and CXCL11.CXCL9, CXCL10 and CXCL11 all elicit their chemotactic functions by interacting with the chemokine receptor CXCR3.Recombinant Mouse MIG/CXCL9 produced in E. coli is a single, non-glycosylated polypeptide chain containing 106 amino acids. A fully biologically active molecule, recombinant Mouse MIG/CXCL9 has a molecular mass of 12.3 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques.
Reconstitution	Reconstituted in ddH2O or PBS at 100ug/ml.
Formulation	Lyophilized after extensive dialysis against PBS.
Molecular Weight	12.3 kDa, observed by reducing SDS-PAGE.
Source	E. coli
Accession Number	P18340
Endotoxin Level	0.2 EU/ug, determined by LAL method.
Notes	For research use only
Bioactivity	The EC50 value of Mouse MIG/CXCL9 on Ca2+ mobilization assay in CHO-K1/Galpha15/mCXCR3 cells (human Galpha15 and mouse CXCR3 stably expressed in CHO-K1 cells) is less than 2 ug/ml.

Synonyms	Small inducible cytokine B9, CXCL9, Gamma interferon-induced monokine, MIG, chemokine (C-X-C motif) ligand 9, CMK, Humig, SCYB9, crg-10, M119, monokine induced by gamma-interferon.
Sequence	MTLVIRNARC SCISTSRGTI HYKSLKDLKQ FAPSPNCNKTEIIATLKNGD QTCLDPDSANVKKLMKEWEK KISQKKKQKR GKKHQKNMKNRKPKTPQSRR RSRKTT

Purity	95% as analyzed by SDS-PAGE.
Storage	Lyophilized recombinant Mouse MIG/CXCL9, remains stable up to 6 months at lower than -70°C from date of receipt. Upon reconstitution, Mouse MIG/CXCL9 should be stable up to 1 week at 4°C or up to 3 months at -20°C.For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles.

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHP18500476-1	IX03343-1	1mg	$1686		Add to Cart
BHP18500476-2	IX03343-25	25ug	$199		Add to Cart
BHP18500476-3	IX03343-5	5ug	$74		Add to Cart

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