Human MEK1 (K97R) (GenBank Accession No. NM_002755), full length with lysine97 to arginine mutation and C-terminal His-tag, MW=44.3 kDa, expressed in E. coli. The K97R mutation prevents ATP binding, making the kinase inactive.
Specific activity: inactive
Immunogen Region
full length
Tag
C-terminal His-tag
Formulation
45 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 10% glycerol, 200 mM imidazole, and 3 mM DTT.
Species
Human
Application
Useful as a substrate of cRAF (RAF1) and other kinases.