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Home / Proteins & Peptide

MCP-5/CCL12, Mouse

SKU : BHP18500424

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iXCells Biotechnologies

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Mfr.No.	IX03283, IX03283-1, IX03283-10, IX03283-50
Description	Monocyte Chemotactic Protein-5(MCP-5), also known as Chemokine (C-C motif) ligand 12(CCL12), is a small cytokine belonging to the CC chemokine family that has been characterized in mice. Due to its similarity with human chemokine MCP-1, sometimes it is called MCP-1-related chemokine. MCP-5 specifically attracts eosinophils, monocytes and lymphocytes.It can signal through the CCR2 receptor.Recombinant Mouse MCP-5/CCL1 produced in CHO cells is a polypeptide chain containing 82 amino acids. A fully biologically active molecule, rmMCP-5/CCL12 has a molecular mass of 11 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques.
Reconstitution	Reconstituted in ddH2O or PBS at 100 ug/ml.
Formulation	Lyophilized after extensive dialysis against PBS.
Molecular Weight	9.3-11 kDa, observed by reducing SDS-PAGE.
Source	CHO
Host	Mouse
Accession Number	Q62401.1
Endotoxin Level	0.2 EU/ug, determined by LAL method.
Notes	For research use only
Bioactivity	The EC50 value of mouse MCP-5/CCL12 on Ca2+ mobilization assay in CHO-K1/G?15/mCCR2 cells (human G?15 and mouse CCR2 stably expressed in CHO-K1 cells) is less than 0.5 ug/ml.

Synonyms	MCP-5,Monocyte Chemotactic Protein-5, CCL12
Sequence	GPDAVSTPVT CCYNVVKQKI HVRKLKSYRR ITSSQCPREAVIFRTILDKE ICADPKEKWV KNSINHLDKT SQTFILEPSCLG

Purity	98% as analyzed by SDS-PAGE.
Storage	Lyophilized recombinant Mouse MCP-5/CCL12 remains stable up to 6 months at lower than -70°C from date of receipt. Upon reconstitution, Mouse MCP-5/CCL12 should be stable up to 1 week at 4°C or up to 2 months at -20°C.

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHP18500424-1	IX03283-1	1mg	$1686		Add to Cart
BHP18500424-2	IX03283-10	10ug	$74		Add to Cart
BHP18500424-3	IX03283-50	50ug	$199		Add to Cart

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