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Home / Proteins & Peptide

MCP?3/MARC/CCL7, Mouse

SKU : BHP18500423

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iXCells Biotechnologies

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Mfr.No.	IX03282, IX03282-1, IX03282-10, IX03282-50
Reconstitution	Reconstituted in ddH2O or PBS at 100 ug/ml.
Description	Chemokine (C-C motif) ligand 7 (CCL7) is a small cytokine that was previously called monocyte-specific chemokine 3 (MCP-3). Due to CCL7 possessing two adjacent N-terminal cysteine residues in its mature form, it is classified within the subfamily of chemokines known as CC chemokines. CCL7 specifically attracts monocytes, and regulates macrophage function. It is produced by certain tumor cell lines and by macrophages. This chemokine is located on chromosome 17 in humans, within a large cluster containing many other CC chemokines and is most closely related to CCL2. CCL7 can signal through the CCR1, CCR2 and CCR3 receptors.Recombinant Mouse MCP?3/MARC/CCL7 produced in CHO cells is a polypeptide chain containing 74 amino acids. A fully biologically active molecule, rmMCP 3/CCL7 has a molecular mass of 8-12 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques.
Formulation	Lyophilized after extensive dialysis against PBS.
Molecular Weight	8~12 kDa, observed by reducing SDS-PAGE.
Source	CHO
Host	Mouse
Accession Number	Q03366.1
Endotoxin Level	0.2 EU/ug, determined by LAL method.
Notes	For research use only
Bioactivity	The EC50 value of mouse MCP 3 MARC/CCL7 on Ca2+ mobilization assay in CHO-K1/ Galpha15/mCCR2 cells (human Galpha15 and mouse CCR2 stably expressed in CHO-K1 cells) is less than 1 ug/ml.

Synonyms	Small inducible cytokine A7, CCL7, Monocyte chemotactic protein 3, MCP-3, Monocyte chemoattractant protein 3, MARC
Sequence	QPDGPNASTC CYVKKQKIPK RNLKSYRRIT SSRCPWEAVIFKTKKGMEVC AEAHQKWVEE AIAYLDMKTP TPKP

Purity	98% as analyzed by SDS-PAGE.
Storage	Lyophilized recombinant Mouse MCP?3/MARC/CCL7 remains stable up to 6 months at lower than -70°C from date of receipt. Upon reconstitution, Mouse MCP?3/MARC/CCL7 should be stable up to 1 week at 4°C or up to 3 months at -20°C.

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHP18500423-1	IX03282-1	1mg	$1872		Add to Cart
BHP18500423-2	IX03282-10	10ug	$112		Add to Cart
BHP18500423-3	IX03282-50	50ug	$199		Add to Cart

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