Human leukotriene A-4 hydrolase, LTA4H, (GenBank Accession No. NM_000895, a.a. 1-611(end) with C-terminal FLAG-tag and His-tag, MW = 71 kDa, expressed in an E. coli cell expression system.
Immunogen Region
1-611 (end)
Tag
C-terminal FLAG-His-tags
Formulation
40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 0.04% Tween-20, 100 mM imidazole, and 20% glycerol.
Species
Human
Application
Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling
Purification
Protein was purified by affinity chromatography.
Notes
Avoid freeze/thaw cycles.
GenBank
NM_000895
Mw(kda)
71 kDa
Synonyms
LTA4, LTA4 hydrolase
Uniprot
P09960
Shipping Temperature
-80°C (dry ice)
Format
Aqueous buffer solution.
Storage
At least 6 months at -80°C.
Reference
1. Snelgrove, R.J., et al., Science 2010: 330(2000):90-94. 2. Stsiapanava, A., et al., PNAS 2014: 111(11):4227-4232