Human KRAS also known as C-K-RAS, CFC2, and K-RAS2A, GenBank Accession No. NM_033360, a.a. 2-186, with Gly12 to Cys mutation and N-terminal His-tag, expressed in an E. coli expression system. MW=23 kDa. The KRAS (G12C) mutant is constitutively active.
Immunogen Region
2-186
Tag
N-terminal His-Tag
Formulation
40 mM Tris-HCl, pH 8.0, 122 mM NaCl, 2.2 mM KCl and 20% glycerol.
Species
Human
Notes
Avoid freeze/thaw cycles.
GenBank
NM_033360
Mw(kda)
23 kDa
Synonyms
C-K-RAS, CFC2, K-RAS2A
Uniprot
P01116
Shipping Temperature
-80°C (dry ice)
Format
Aqueous buffer solution
Storage
At least 6 months at -70°C.
Reference
1. Lito, P., et al., Science. 2016 Feb;351(6273):604-608. 2. Dogan, S., et al., Clinical Cancer Research. 2012 Nov;18(22):6169-6177.