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Home / Proteins & Peptide

Jak2 (JH1 domain), His-tag

SKU : BHP18200247

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BPS Bioscience

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Mfr.No.	40450
Description	Human Jak2 (GenBank Accession No. NM_004972), (a.a. 808-end) with N-terminal His-tag, MW=42.5 kDa, expressed in a baculovirus expression system. Host cell line: Sf9 cells Specific activity: 118 pmol/min/ug.
Immunogen Region	808-end
Tag	N-terminal His-tag
Formulation	40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 3 mM DTT, 20% glycerol, and 200 mM imidazole
Species	Human
Application	Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling
Notes	50 mM HEPES (pH 7.5), 10 mM MgCl₂, 1 mM EGTA, 200 uM ATP, 0.01% Brij-35, and 2 uM substrate (Tyr 4, Invitrogen) at room temperature for 1 hour. Developer solution was added to reaction and reaction was stopped after 1 hour of incubation at RT. Avoid freeze/thaw cycles.
GenBank	NM_004972
Mw(kda)	42.5 kDa

Synonyms	JAK2, Janus kinase-2, Just Another Kinase 2
Uniprot	O60674

Shipping Temperature	-80°C (dry ice)
Format	Aqueous buffer solution
Storage	At least 6 months at -80°C.

Reference	1. Tono,C.,et al., Leukemia 19 (10), 1843-1844 (2005). 2. Goerttler,P.S., et al., Blood 106 (8), 2862-2864(2005).

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP18200247	40450	20 ug	$445.50		Add to Cart

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