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Home / Proteins & Peptide

Jak1, GST-tag

SKU : BHP18200246

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Mfr.No.	40449
Description	Human Jak1 (Janus kinase 1), also known as JTK3, GenBank Accession No. NM_002227, a.a. 866-1154(end) with N-terminal GST-Tag, MW= 59 kDa, expressed in Sf9 cells via a baculovirus expression system. Host cell line: Sf9 cells Specific activity: 1.0 pmol/min/ug.
Immunogen Region	866-1154 (end)
Tag	N-terminal GST-tag
Formulation	40 mM Tris-HCl pH 8.0, 110 mM NaCl, 2.2 mM KCl, 3 mM DTT, 16 mM glutathione and 20% glycerol.
Species	Human
Application	Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling
Notes	Enzyme reaction is conducted at 30°C for 1 hour in a buffer containing 50 mM HEPES (pH 7.5), 10 mM MgCl₂, 1 mM EGTA, 200 uM ATP, 0.01% Brij-35 and 2 uM substrate (Tyr6, Invitrogen) using Z-Lyte assay conditions. Avoid freeze/thaw cycles.
GenBank	NM_002227
Mw(kda)	59 kDa

Synonyms	JAK1, Janus kinase-1, Just Another Kinase 1, JTK3
Uniprot	P23458

Shipping Temperature	-80°C (dry ice)
Format	Aqueous buffer solution
Storage	At least 6 months at -80°C.

Reference	1. Rodig, S.J., et al. (1998). Cell 93 (3): 373-8. 2. Haan, C., et al. (2001). J. Biol. Chem. 276 (40): 37451-8. 3. Miyazaki, T., et al. (1994). Science 266 (5187): 1045-7

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP18200246	40449	10 ug	$412.50		Add to Cart

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