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Home / Proteins & Peptide

IP-10/CRG-2/CXCL10, Rat

SKU : BHP18500422

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iXCells Biotechnologies

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Mfr.No.	IX03281, IX03281-1, IX03281-25, IX03281-5
Reconstitution	Reconstituted in ddH2O or PBS at 100 ug/ml.
Description	C-X-C motif chemokine 10 (CXCL10) also known as interferon gamma-induced protein 10 (IP-10) or small-inducible cytokine B10, is originally identified as an IFN-gamma-inducible gene in monocytes, fibroblasts and endothelial cells. It has since been shown that IP-10 mRNA is also induced by LPS, IL-1beta, TNF-alpha, IL-12 and viruses. Additional cell types that have been shown to express IP-10 include activated T-lymphocytes, splenocytes, keratinocytes, osteoblasts, astrocytes, and smooth muscle cells. IP-10 is also expressed in psoriatic and lepromatous lesions of the skin. Recombinant rat IP-10/CRG-2/CXCL10 produced in HEK 293 cells is a polypeptide chain containing 77 amino acids. A fully biologically active molecule, rr IP-10/CRG-2/CXCL10 has a molecular mass of 8.7 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques.
Formulation	Lyophilized after extensive dialysis against PBS.
Molecular Weight	8.7 kDa, observed by reducing SDS-PAGE.
Source	HEK 293
Host	Rat
Accession Number	P48973
Endotoxin Level	0.2 EU/ug, determined by LAL method.
Notes	For research use only
Bioactivity	The EC50 value of rat IP-10/CRG-2/CXCL10 on Ca2+ mobilization assay in CHO-K1/Galpha15/rCXCR3 cells (human Galpha15 and rat CXCR3 stably expressed in CHO-K1 cells) is less than 300 ng/ml.

Synonyms	Small inducible cytokine B10, CXCL10, 10 kDa interferon-gamma-induced protein, Gamma-IP10, IP-10, chemokine (C-X-C motif) ligand 10, C7, IFI10, INP10, crg-2, mob-1, SCYB10, gIP-10
Sequence	IPLARTVRCT CIDFHEQPLR PRAIGKLEII PASLSCPHVEIIATMKKNNE KRCLNPESEA IKSLLKAVSQ RRSKRAP

Purity	98% as analyzed by SDS-PAGE.
Storage	Lyophilized recombinant Rat IP-10/CRG-2/CXCL10 remains stable up to 6 months at lower than -70°C from date of receipt. Upon reconstitution, Rat IP-10/CRG-2/CXCL10 should be stable up to 1 week at 4°C or up to 3 months at -20°C.

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHP18500422-1	IX03281-1	1mg	$1686		Add to Cart
BHP18500422-2	IX03281-25	25ug	$124		Add to Cart
BHP18500422-3	IX03281-5	5ug	$50		Add to Cart

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