Human Interleukin-17A (IL-17A), also known as CD217 and CANDF5, GenBank Accession No. NM_ 014339, a.a 33-320, fused at the C-terminus of the Fc portion of human IgG1, with C-terminal Avi-tag, expressed in a HEK293 cell expression system, MW=62 kDa. This protein runs at a higher MW by SDS-PAGE due to glycosylation.
host species: human
Host species: human
Host cell line: HEK293
Immunogen Region
33-320
Tag
C-terminal Fc-Avi-tag
Formulation
8 mM Phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol.
Species
Human
Application
Useful for studying protein binding and screening small molecules for drug discovery.
Notes
IL-17RA-IL-17A(B) binding activity was measured using the IL-17RA:IL-17A(Biotin) Binding Assay Kit, Biohippo #79891 and Anti-IL-17A Antibody, Biohippo #91015.
Avoid freeze/thaw cycles.
GenBank
NM_ 014339
Mw(kda)
62 kDa
Synonyms
CD217, IL17R, IMD51, CANDF5, CDw217, hIL-17R
Uniprot
Q96F46
Shipping Temperature
-80°C (dry ice)
Format
Aqueous buffer solution
Storage
At least 6 months at -80°C.
Reference
1. Wright, J.F., et. al. J. Immun. 2008; 181(4): 2799-2805. 2. Rickel, E.A., et al., J. Immun. 2008; 181(6): 4299-4310.