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Home / Proteins & Peptide

IL-15, Human

SKU : BHP18500447

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Mfr.No.	IX03308, IX03308-1, IX03308-10, IX03308-50
Description	Interleukin-15 (IL-15) is a cytokine with structural similarity to IL-2. Like IL-2, IL-15 binds to and signals through a complex composed of IL-2/IL-15 receptor beta chain (CD122) and the common gamma chain (gamma-C, CD132). IL-15 is secreted by mononuclear phagocytes (among other cells) following infection by virus. This cytokine induces cell proliferation of natural killer cells, which are cells of the innate immune system whose principal role is to kill virally infected cells. IL-15 can stimulate the proliferation of T-lymphocytes. Stimulation by IL-15 occurs following its interaction with IL-15Ralpha. This interaction may enhance IL-15 sinteraction with IL15Rbetagammac.Recombinant HumanInterleukin-15 produced in E. coli is a single non-glycosylated polypeptide chain containing 114 amino acids. A fully biologically active molecule, rhIL-15 has a molecular mass of 12.8 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques.
Reconstitution	Reconstituted in ddH2O or PBS at 100 ug/ml.
Formulation	Lyophilized after extensive dialysis against PBS.
Molecular Weight	12.8 kDa, observed by reducing SDS-PAGE.
Source	E. coli
Accession Number	P40933
Endotoxin Level	0.2 EU/ug, determined by LAL method.
Notes	For research use only
Bioactivity	ED50 0.5 ng/ml, determined by the dose-dependent stimulation of the proliferation of CTLL-2 cells, corresponding to a specific activity of 2 x 106 units/mg.

Synonyms	IL15, IL-T
Sequence	Asn49-Ser162 (Accession#: P40933)

Purity	95% as analyzed by SDS-PAGE.
Storage	Lyophilized recombinant Human Interleukin-15 (rhIL-15) remains stable up to 6 months at lower than -70°C from date of receipt. Upon reconstitution, rhIL-15 should be stable up to 1 week at 4°C or up to 3 months at -20°C.

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHP18500447-1	IX03308-1	1mg	$2185		Add to Cart
BHP18500447-2	IX03308-10	10ug	$112		Add to Cart
BHP18500447-3	IX03308-50	50ug	$263		Add to Cart

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