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Home / Proteins & Peptide

IFN-gamma, Human(CHO-expressed)

SKU : BHP18500192

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iXCells Biotechnologies

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Mfr.No.	IX02986, IX02986-1, IX02986-10, IX02986-50
Description	Human Interferon gamma (hIFN-gamma) is amacrophage-activating factor and the lone member of Interferon type II. The active form of IFN-gamma is an antiparallel dimer that interacts with the receptor IFN-gammaR1 and sets off IFN-gamma/JAK/STAT pathway. IFN-gamma signaling does diverse biological functions primarily related to host defense and immune regulation, including antiviral and antibacterial defense, apoptosis, inflammation, and innate and acquired immunity. While IFN-gammainduced inflammatory cascade summons a variety of immune-related cell types, such as macrophages, natural killer (NK) cells and cytotoxic T lymphocytes (CTLs), IFN-gamma is also implicated in resistance to NK cell and CTL responses and in immune escape in a variety of cancers.
Reconstitution	Reconstituted in ddH2O or PBS at 100 ug/ml.
Formulation	Lyophilized after extensive dialysis against PBS.
Molecular Weight	15-25 kDa, observed by non-reducing SDS-PAGE.
Source	CHO
Host	Human
Endotoxin Level	0.2 EU/ug, determined by LAL method.
Notes	For research use only
Bioactivity	ED50 2 ng/ml, measured in a cytotoxicity assay using HT-29 cells, corresponding to a specific activity of 5x105 units/mg.

Synonyms	Immune Interferon, type II interferon, T cell interferon, MAF
Sequence	QDPYVKEAEN LKKYFNAGHS DVADNGTLFL GILKNWKEESDRKIMQSQIV SFYFKLFKNF KDDQSIQKSV ETIKEDMNVKFFNSNKKKRD DFEKLTNYSV TDLNVQRKAI HELIQVMAELSPAAKTGKRK RSQMLFRGRR ASQ

Purity	95% as analyzed by SDS-PAGE and HPLC.
Storage	Lyophilized recombinant Human Interferon gamma (IFN-gamma) remains stable up to 6 months at lower than -70°C from date of receipt. Upon reconstitution, rh IFN-gamma should be stable up to 1 week at 4°C or up to 2 months at -20°C.

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHP18500192-1	IX02986-1	1mg	$531		Add to Cart
BHP18500192-2	IX02986-10	10ug	$32		Add to Cart
BHP18500192-3	IX02986-50	50ug	$75		Add to Cart

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