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Home / Proteins & Peptide

IDO1, His-tag (Human)

SKU : BHP18201583

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Mfr.No.	71182-2
Description	Human IDO1 enzyme, also known as Indoleamine 2,3-dioxygenase 1, GenBank Accession No. NM_002164, a.a. 2-403(end) with an N-terminal His-tag, expressed in the presence of hemin in an E. coli cell expression system. MW = 46 kDa.
Immunogen Region	2-403(end)
Tag	N-terminal His-tag
Formulation	40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 20% glycerol
Species	Human
Application	Useful for studying enzyme kinetics, substrate specificity, and screening inhibitors.
Notes	IDO1 enzyme activity was confirmed using the IDO1 Inhibitor Screening Assay Kit (BPS Cat. #72021) and following the protocol provided with the kit. Avoid freeze/thaw cycles. Storing diluted protein is not recommended, if necessary, use carrier protein (BSA 0.1 - 0.5%).
GenBank	NM_002146
Mw(kda)	46 kDa

Synonyms	Indoleamine 2,3-dioxygenase 1
Uniprot	P14902

Shipping Temperature	-80°C (dry ice)
Format	Aqueous buffer solution
Storage	At least 6 months at -80°C.

Reference	1. Lob, S. et al., Cancer Immunol. Immunother. 2009; 58(1): 153-157. 2. Liu, X. et al., Blood. 2010; 115(17): 3520-3530. 3. Flick, H.E., et al., Int. Nat. J. of Tryptophan Res. 2013; 6: 35-45.Application Reference(s): 1. Gao, D., and Li, Y. Bioorganic & Medicinal Chemistry 25(14), July 2017, 3780-3791 Identification and preliminary structure-activity relationships of 1-Indanone derivatives as novel indoleamine-2,3-dioxygenase 1 (IDO1) inhibitors (2017)

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP18201583	71182-2	500 ug	$3481.50		Add to Cart

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