Human herpesvirus entry mediator A, also known as HVEM, TNFRSF14, CD270, and HVEA, GenBank Accession No. NM_003820, a.a. 37-202 fused to human IgG1 Fc, expressed in a HEK293 cell expression system. MW = 44.2 kDa. This protein runs at a higher M.W. by SDSPAGE due to glycosylation.
Formulation
40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol
Species
Human
Application
Useful for the study of protein-protein interaction and in vitro and in vivo protein function studies.
Endotoxin Level
<1 EU/ug
Notes
The aggregation state of this product has been confirmed to be<10%. Avoid freeze/thaw cycles. Protein may be diluted to>=100 ug/ml in PBS + glycerol and stored at -80°C.
GenBank
NM_003820
Mw(kda)
44.2 kDa
Synonyms
HVEM, TNFRSF14, CD270, HVEA, TR2, LIGHTR
Uniprot
Q92956
Shipping Temperature
-80°C (dry ice)
Format
Aqueous buffer solution
Storage
At least 6 months at -80°C.
Reference
1. Derre, L., et al. J. Clin. Invest. 2010,120(1): 157-167. 2. Steinberg, M.W., et al. J. Exp.Med. 2008, 205(6): 1463-1476.