Human TIM3 Protein, mFc-His Tag

Mfr.No.	PME100030
Description	Recombinant human TIM3 protein with C-terminal mouse Fc and 6×His tag
Background	The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positIVe T helper lymphocytes can be dIVIded into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitIVIty reactions, whereas, Th2 cells are involved in the control of eXtracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage actIVation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance.
Tag	C-Mouse Fc and 6×His tag
Formulation	Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Molecular Weight	The protein has a predicted molecular mass of 47.5 kDa after removal of the signal peptide.
Host	HEK293
Notes	Research use only

Purity	The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
Storage	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

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SKU	Supplier No.	Size	Your price
BHP18100040	PME100030	100 ug	$430	Add to Cart
BHP18100040	PME100030	50 ug	$290	Add to Cart
BHP18100040	PME100030	10 ug	$75	Add to Cart