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Home / Proteins & Peptide

Human PTEN / Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN Recombinant Protein

SKU : BHP13800275

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	R14875h
Alternative Names	Mutated in multiple advanced cancers 1,Phosphatase and tensin homolog,MMAC1,TEP1
Source	E.coli
Species	Homo Sapiens (Human)
Accession Number	P60484
Endotoxin Level	<0.10 EU per 1 μg of the protein by the LAL method
Concentration	Reconstitution Dependent
Form	Liquid
Protein Name	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
Entry Function	Isoform alpha: Functional kinase, like isoform 1 it antagonizes the PI3K-AKT/PKB signaling pathway. Plays a role in mitochondrial energetic metabolism by promoting COX activity and ATP production, via collaboration with isoform 1 in increasing protein levels of PINK1.
Mw(kda)	12.76

Subunit	Monomer. The unphosphorylated form interacts with the second PDZ domain of AIP1 and with DLG1 and MAST2 in vitro (PubMed:10646847, PubMed:10760291, PubMed:11707428). Interacts with MAGI2, MAGI3, MAST1 and MAST3, but neither with MAST4 nor with DLG5; interaction with MAGI2 increases protein stability (PubMed:10748157, PubMed:15951562). Interacts with NEDD4 (PubMed:17218260). Interacts with NDFIP1 and NDFIP2; in the presence of NEDD4 or ITCH, this interaction promotes PTEN ubiquitination (PubMed:25801959, PubMed:20534535). Interacts (via C2 domain) with FRK (PubMed:19345329). Interacts with USP7; the interaction is direct (PubMed:18716620). Interacts with ROCK1 (By similarity). Interacts with XIAP/BIRC4 (PubMed:19473982). Interacts with STK11; the interaction phosphorylates PTEN (PubMed:15987703).
Gene Name	PTEN
Sequence	288-403aa

Purity	Greater than 95% by SDS-PAGE
Storage	Store at -20°C. (Avoid repeated freezing and thawing.)
Storage Buffer	50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole,10%glycerol(PH8.0)

Applications	Par, ELISA, AP, WB

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SKU	Supplier No.	Size	Your price	Quantity
BHP13800275	R14875h	50µg	$637.78		Add to Cart
BHP13800275	R14875h	100µg	$904.44		Add to Cart
BHP13800275	R14875h	200µg	$1348.89		Add to Cart
BHP13800275	R14875h	0.5mg	$1971.11		Add to Cart
BHP13800275	R14875h	1mg	$2682.22		Add to Cart
BHP13800275	R14875h	5mg	$4637.78		Add to Cart
BHP13800275	R14875h	10mg	$6148.89		Add to Cart

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