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Home / Proteins & Peptide

Human PSMA Protein, mFc Tag

SKU : BHP18100400

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DIMA Biotechnology

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Mfr.No.	PME100546
Description	Recombinant human PSMA protein with N-terminal mouse Fc tag
Background	This gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboXypeptidase on different alternatIVe substrates, including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is eXpressed in a number of tissues such as prostate, central and peripheral nervous system and kidney. A mutation in this gene may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. EXpression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate eXcitotoXicity. In the prostate the protein is up-regulated in cancerous cells and is used as an effectIVe diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region. AlternatIVe splicing gIVes rise to multiple transcript variants encoding several different isoforms.
Tag	N-Mouse Fc
Formulation	Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Molecular Weight	The protein has a predicted molecular mass of 105.8 kDa after removal of the signal peptide.The apparent molecular mass of mFc-PSMA is approXimately 130 kDa due to glycosylation.
Host	HEK293
Notes	Research use only

Synonyms	FGCP, FOLH, GCP2, GCPII, mGCP, NAALAD1, NAALAdase, PSM, PSMA
Uniprot	Q04609
Target	PSMA

Purity	The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
Storage	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

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SKU	Supplier No.	Size	Your price	Quantity
BHP18100400	PME100546	100 ug	$400		Add to Cart
BHP18100400	PME100546	50 ug	$270		Add to Cart
BHP18100400	PME100546	10 ug	$70		Add to Cart

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