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Home / Proteins & Peptide

Human PINK1 / Serine/threonine-protein kinase PINK1, mitochondrial Recombinant Protein

SKU : BHP13800227

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	R15235h
Alternative Names	BRPK,PTEN-induced putative kinase protein 1
Source	E.coli
Species	Homo Sapiens (Human)
Accession Number	Q9BXM7
Endotoxin Level	<0.10 EU per 1 μg of the protein by the LAL method
Concentration	Reconstitution Dependent
Form	Liquid
Protein Name	Serine/threonine-protein kinase PINK1, mitochondrial
Entry Function	Protects against mitochondrial dysfunction during cellular stress by phosphorylating mitochondrial proteins. Involved in the clearance of damaged mitochondria via selective autophagy (mitophagy) by mediating activation and translocation of PARK2. Targets PARK2 to dysfunctional depolarized mitochondria through the phosphorylation of MFN2. Activates PARK2 in 2 steps: (1) by mediating phosphorylation at 'Ser-65' of PARK2 and (2) mediating phosphorylation of ubiquitin, converting PARK2 to its fully-active form (PubMed:24660806, PubMed:24751536, PubMed:24784582, PubMed:25527291).
Mw(kda)	22.66

Subunit	Interacts with PARK2. Interacts with FBXO7. Forms a complex with PARK2 and PARK7 (PubMed:19229105).
Gene Name	PINK1
Sequence	260-465aa

Purity	Greater than 95% by SDS-PAGE
Storage	Store at -20°C. (Avoid repeated freezing and thawing.)
Storage Buffer	50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole,10%glycerol(PH8.0)

Applications	Par, ELISA, AP, WB

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SKU	Supplier No.	Size	Your price	Quantity
BHP13800227	R15235h	50µg	$637.78		Add to Cart
BHP13800227	R15235h	100µg	$904.44		Add to Cart
BHP13800227	R15235h	200µg	$1348.89		Add to Cart
BHP13800227	R15235h	0.5mg	$1971.11		Add to Cart
BHP13800227	R15235h	1mg	$2682.22		Add to Cart
BHP13800227	R15235h	5mg	$4637.78		Add to Cart
BHP13800227	R15235h	10mg	$6148.89		Add to Cart

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