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Home / Proteins & Peptide

Human/Mouse ERK2 (K52R), Inactive, His-tag

SKU : BHP18200148

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Mfr.No.	40056
Description	Human/Mouse ERK2/MAPK2 (K52R) (GenBank Accession No. NM_0011949), full length with mutation on lysine52 to arginine and with an N-terminal His-tag, MW=42 kDa, expressed in E. coli . The K52R mutation prevents ATP binding, making the kinase inactive. Specific activity: inactive
Immunogen Region	full length
Tag	N-terminal His-tag
Formulation	45 mM Tris-HCl, pH 8.0, 124 mM NaCl, 2.4 mM KCl, 125 mM imidazole, 3 mM DTT, 10% glycerol.
Species	Mouse
Application	Useful as a substrate for MEK1.
Notes	The human and mouse versions of this protein share 100% amino acid homology. Avoid freeze/thaw cycles.
GenBank	NM_0011949
Mw(kda)	42 kDa

Synonyms	ERK2, MAPK1, mitogen-activated protein kinase 1, Extracellular Signal-Regulated Kinase 2, PRKM

Shipping Temperature	-80°C (dry ice)
Format	Aqueous buffer solution
Storage	At least 6 months at -80°C.

Reference	1. Robinson, M.J., et al. Biochemistry. 1996 May 7;35(18):5641-6. 2. Mitsushima, M. et al. Cell Res. 313 (9), 1830- 1838 (2007). 3. Wille, L. et al. Mol. Immunol. 44 (12), 3085- 3091 (2007).

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SKU	Supplier No.	Size	Your price	Quantity
BHP18200148	40056	100 ug	$407		Add to Cart

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