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Home / Proteins & Peptide

Human KLHL22 / Kelch-like protein 22 Recombinant Protein

SKU : BHP13800177

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	R7176h
Source	E.coli
Species	Homo Sapiens (Human)
Accession Number	Q53GT1
Endotoxin Level	<0.10 EU per 1 μg of the protein by the LAL method
Concentration	Reconstitution Dependent
Form	Liquid
Protein Name	Kelch-like protein 22
Entry Function	Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for chromosome alignment and localization of PLK1 at kinetochores. The BCR(KLHL22) ubiquitin ligase complex mediates monoubiquitination of PLK1, leading to PLK1 dissociation from phosphoreceptor proteins and subsequent removal from kinetochores, allowing silencing of the spindle assembly checkpoint (SAC) and chromosome segregation. Monoubiquitination of PLK1 does not lead to PLK1 degradation.
Mw(kda)	23.1

Subunit	Component of the BCR(KLHL22) E3 ubiquitin ligase complex, at least composed of CUL3, KLHL22 and RBX1. Interacts with PLK1.
Gene Name	KLHL22
Sequence	371-580aa

Purity	Greater than 95% by SDS-PAGE
Storage	Store at -20°C. (Avoid repeated freezing and thawing.)
Storage Buffer	50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole,10%glycerol(PH8.0)

Applications	Par, ELISA, AP, WB

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SKU	Supplier No.	Size	Your price	Quantity
BHP13800177	R7176h	50µg	$637.78		Add to Cart
BHP13800177	R7176h	100µg	$904.44		Add to Cart
BHP13800177	R7176h	200µg	$1348.89		Add to Cart
BHP13800177	R7176h	0.5mg	$1971.11		Add to Cart
BHP13800177	R7176h	1mg	$2682.22		Add to Cart
BHP13800177	R7176h	5mg	$4637.78		Add to Cart
BHP13800177	R7176h	10mg	$6148.89		Add to Cart

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