Human IL13(35-146) Protein, hFc Tag

Mfr.No.	PME101128
Description	Recombinant human IL13(35-146) protein with C-terminal human Fc tag
Background	This gene encodes an immunoregulatory cytokine produced primarily by actIVated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II eXpression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage actIVIty, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4. (proVIded by RefSeq, Jul 2008)
Tag	C-Human Fc tag
Formulation	Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Molecular Weight	The protein has a predicted molecular mass of 38.4 kDa after removal of the signal peptide. The apparent molecular mass of IL13(35-146)-hFc is approXimately 33-53 kDa due to glycosylation.
Host	HEK293
Notes	Research use only

Purity	The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
Storage	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

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SKU	Supplier No.	Size	Your price
BHP18100740	PME101128	100 ug	$550	Add to Cart
BHP18100740	PME101128	50 ug	$375	Add to Cart
BHP18100740	PME101128	10 ug	$100	Add to Cart