Human IGF-1R Protein, His Tag

Mfr.No.	PME100814
Description	Recombinant human IGF-1R protein with C-terminal 6×His tag
Background	This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase actIVIty. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overeXpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell surVIVal. AlternatIVely spliced transcript variants encoding distinct isoforms have been found for this gene. (proVIded by RefSeq, May 2014)
Tag	C-6×His tag
Formulation	Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Molecular Weight	The protein has a predicted molecular mass of 103.7 kDa after removal of the signal peptide. The apparent molecular mass of IGF-1R-His is approXimately 130-150 kDa due to glycosylation.
Host	HEK293
Notes	Research use only

Purity	The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
Storage	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

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SKU	Supplier No.	Size	Your price
BHP18100571	PME100814	100 ug	$360	Add to Cart
BHP18100571	PME100814	50 ug	$240	Add to Cart
BHP18100571	PME100814	10 ug	$60	Add to Cart