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Home / Proteins & Peptide

Human GRB2/ Growth factor receptor-bound protein 2 Recombinant Protein

SKU : BHP13800358

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	R2740h
Alternative Names	GRB2-associated binder 2,Growth factor receptor bound protein 2-associated protein 2,pp100,KIAA0571
Source	E.coli
Species	Homo Sapiens (Human)
Accession Number	Q9UQC2
Endotoxin Level	<0.10 EU per 1 μg of the protein by the LAL method
Concentration	Reconstitution Dependent
Form	Liquid
Protein Name	GRB2-associated-binding protein 2
Entry Function	Adapter protein which acts downstream of several membrane receptors including cytokine, antigen, hormone, cell matrix and growth factor receptors to regulate multiple signaling pathways. Regulates osteoclast differentiation mediating the TNFRSF11A/RANK signaling. In allergic response, it plays a role in mast cells activation and degranulation through PI-3-kinase regulation. Also involved in the regulation of cell proliferation and hematopoiesis.
Mw(kda)	25.19

Subunit	Interacts with SHC1; may mediate interaction with receptors (By similarity). Interacts with SYK (By similarity). Interacts with PI-3 kinase. Interacts with GRB2 (via SH3 2 domain). Interacts (phosphorylated) with PTPN11. Interacts with TNFRSF11A (via cytoplasmic domain). Interacts (phosphorylated) with 14-3-3 family proteins SFN, YWHAB, YWHAE, YWHAG, YWHAH, YWHAQ and YWHAZ; prevents interaction with GRB2 and attenuates GAB2 signaling. Interacts with HCK.
Gene Name	GRB2
Sequence	448-676aa

Purity	Greater than 95% by SDS-PAGE
Storage	Store at -20°C. (Avoid repeated freezing and thawing.)
Storage Buffer	50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole,10%glycerol(PH8.0)

Applications	Par, ELISA, AP, WB

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SKU	Supplier No.	Size	Your price	Quantity
BHP13800358	R2740h	50µg	$637.78		Add to Cart
BHP13800358	R2740h	100µg	$904.44		Add to Cart
BHP13800358	R2740h	200µg	$1348.89		Add to Cart
BHP13800358	R2740h	0.5mg	$1971.11		Add to Cart
BHP13800358	R2740h	1mg	$2682.22		Add to Cart
BHP13800358	R2740h	5mg	$4637.78		Add to Cart
BHP13800358	R2740h	10mg	$6148.89		Add to Cart

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