Human FCGR3A Protein (F176V), His Tag

Mfr.No.	PME100069
Background	This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody compleXes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is eXpressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is eXpressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent VIral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. AlternatIVely spliced transcript variants encoding different isoforms have been found for this gene.
Tag	C-6×His tag
Description	Recombinant human FCGR3A protein (F176V) with C-terminal 6×His tag
Formulation	Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Molecular Weight	The protein has a predicted molecular mass of 22.3 kDa after removal of the signal peptide.
Host	HEK293
Notes	Research use only

Purity	The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
Storage	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

Have you used this product?

SKU	Supplier No.	Size	Your price
BHP18100064	PME100069	100 ug	$360	Add to Cart
BHP18100064	PME100069	50 ug	$240	Add to Cart
BHP18100064	PME100069	10 ug	$60	Add to Cart