Human CD226 antigen alsoknown as DNAX accessory molecule 1(DNAM-1), GenBank Accession No.NM_006566, a.a. 19-247 fused to Fc regionof human IgG1, expressed in a HEK293 cellexpression system. MW = 52.8 kDa(monomer). This protein runs at a higherMW by SDS-PAGE due to glycosylation.
Immunogen Region
19-247
Tag
Fc fusion (Human IgG1)
Formulation
8 mM Na Phosphate pH 7.4, 110 mM NaCl, 2.2 mM KCl and 20% glycerol.
Species
Human
Application
Useful for studying protein binding and for screening small molecules and antibodies.
Notes
The aggregation state of this product has been confirmed to be<10%. Avoid freeze/thaw cycles. Protein may be diluted to>=100 ug/ml in PBS + glycerol and stored at -80°C.
GenBank
NM_006566
Mw(kda)
52.8 kDa
Synonyms
DNAX accessory molecule 1 (DNAM-1)
Uniprot
Q15762
Shipping Temperature
-80°C (dry ice)
Format
Aqueous buffer solution
Storage
At least 6 months at -80°C.
Reference
1. Bottino, C., et al., J. Exp. Med. 2003; 198(4): 557-567. 2. Hafler, J., et al., Genes Immun. 2009; 10: 5-10.