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Home / Proteins & Peptide

Human CASP3 / Caspase-3 Recombinant Protein

SKU : BHP13800057

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	R0626h
Alternative Names	Apopain,Cysteine protease CPP32,CPP-32,Protein Yama,SREBP cleavage activity 1,SCA-1,CPP32
Source	E.coli
Species	Homo Sapiens (Human)
Accession Number	NP_004337/ncbi
Endotoxin Level	<0.10 EU per 1 μg of the protein by the LAL method
Concentration	Reconstitution Dependent
Form	Liquid
Protein Name	Caspase-3
Entry Function	Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp- ; -Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage.
Mw(kda)	9.24

Subunit	Heterotetramer that consists of two anti-parallel arranged heterodimers, each one formed by a 17 kDa (p17) and a 12 kDa (p12) subunit. Interacts with BIRC6/bruce.
Gene Name	CASP3
Sequence	29-112aa

Purity	Greater than 95% by SDS-PAGE
Storage	Store at -20°C. (Avoid repeated freezing and thawing.)
Storage Buffer	50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole,10%glycerol(PH8.0)

Applications	Par, ELISA, AP, WB

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SKU	Supplier No.	Size	Your price	Quantity
BHP13800057	R0626h	50µg	$637.78		Add to Cart
BHP13800057	R0626h	100µg	$904.44		Add to Cart
BHP13800057	R0626h	200µg	$1348.89		Add to Cart
BHP13800057	R0626h	0.5mg	$1971.11		Add to Cart
BHP13800057	R0626h	1mg	$2682.22		Add to Cart
BHP13800057	R0626h	5mg	$4637.78		Add to Cart
BHP13800057	R0626h	10mg	$6148.89		Add to Cart

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