Human AGR2 Protein, hFc Tag

Mfr.No.	PME100783
Description	Recombinant human AGR2 protein with C-terminal human Fc tag
Background	This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically actIVe thioredoXin domain, and a C-terminal ER-retention sequence. This protein plays a role in cell migration, cellular transformation and metastasis and is as a p53 inhibitor. As an ER-localized molecular chaperone, it plays a role in the folding, trafficking, and assembly of cysteine-rich transmembrane receptors and the cysteine-rich intestinal gylcoprotein mucin. This gene has been implicated in inflammatory bowel disease and cancer progression. (proVIded by RefSeq, Mar 2017)
Tag	C-Human Fc tag
Formulation	Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Molecular Weight	The protein has a predicted molecular mass of 44.0 kDa after removal of the signal peptide. The apparent molecular mass of AGR2-hFc is approXimately 35-55 kDa due to glycosylation.
Host	HEK293
Notes	Research use only

Purity	The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
Storage	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

Have you used this product?

SKU	Supplier No.	Size	Your price
BHP18100694	PME100783	100 ug	$568	Add to Cart
BHP18100694	PME100783	50 ug	$388	Add to Cart
BHP18100694	PME100783	10 ug	$103	Add to Cart