Human induced Heat Shock Protein 70 (Q435A), also known as induced HSP70 and HSP70i, with a Gln to Ala mutation on a.a. 435 of the HSP70 protein. GenBank Accession No. NM_005345, a.a. 1-641(end) with C-terminal His-tag, MW = 70.8 kDa, expressed in an E. coli expression system.
Immunogen Region
full length
Tag
C-terminal His-tag
Formulation
40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 0.04% Tween-20, 175 mM Imidazole and 20% glycerol.
Species
human
Application
Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling
Notes
Avoid freeze/thaw cycles.
GenBank
NM_005345
Mw(kda)
70.8 kDa
Synonyms
heat shock protein 70, induced hsp70, hsp70i
Uniprot
P08107
Shipping Temperature
-80°C (dry ice)
Format
Aqueous buffer solution
Storage
At least 6 months at -80°C.
Reference
1. Lee K.J. et al., Exp. Mol. Med. 40 (6), 658-668 (2008). 2. Birtas-Atesoglu E. et al., Clin. Exp. Rheumatol. 26, S96-S98 (2008).