Human Histone 3(HIST1H3E), GenBank Accession No.NM_003532, a.a. 2-136(end) with K27Mmutation and N-terminal His-tag, MW =16.2 kDa, expressed in an E. coliexpression system.
Host cell line: E. coli
Immunogen Region
2-136(end) with K27M mutation
Tag
N-terminal His-tag
Formulation
8 mM PBS pH 7.4, 110 mM NaCl, 2.2 mM KCl and 20% glycerol
Mutation
K27M
Species
Human
Application
Useful as a substrate for methyltransferases or acetyltransferases and for screening inhibitors and selectivity profiling for drug discovery.
Notes
Avoidfreeze/thaw cycles. Storing diluted proteinis not recommended, if necessary, usecarrier protein (BSA 0.1 - 0.5%).