Human Histone 2A, GenBank Accession No. NM_033445, a.a. 2-130(end) with N-terminal His-tag, MW = 14.8 kDa, expressed in an E. coli expression system.
Host cell line: E. coli
Immunogen Region
2-130(end)
Tag
N-terminal His-tag
Formulation
50 mM Tris-HCl, pH 8.0, 150 mM NaCl, 10% glycerol, 1 mM PMSF and 1 mM DTT.
Species
Human
Application
Useful as a substrate for histone methyltransferase and acetyltransferase assays. Ideal for screening small molecular inhibitors of histone modifying enzymes for drug discovery and HTS applications.
Notes
Avoid freeze/thaw cycles.
GenBank
NM_033445
Mw(kda)
14.8 kDa
Synonyms
HIST1H2AI, H2A.1, histone H2A
Uniprot
Q7L7L0
Shipping Temperature
-80°C (dry ice)
Format
Aqueous buffer solution
Storage
At least 6 months at -80°C.
Reference
1. Osley, M.A. Brief Funct. Genomic Proteomic 5(3):179-89 (2006). 2. Wyrick, J.J. and Parra, M.A. Biochim Biophys Acta. 1789(1):37-44 (2009). 3. Zhou, W., et al. Int J Biochem Cell Biol. 41(1):12-5 (2009).