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Home / Proteins & Peptide

HDAC4, GST-tag, His-tag

SKU : BHP18200304

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BPS Bioscience

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Mfr.No.	50004
Description	Human HDAC4 (GenBank Accession No. NM_006037), a.a. 627-1084 (end) with N-terminal GST-tag and C-terminal His-tag, MW= 76 kDa, expressed in baculovirus expression system. Host cell line: Sf9 cells Specific activity: >=100,000 pmol/min/ug.
Immunogen Region	627-1084 (end)
Tag	N-terminal GST-tag, C-terminal His-tag
Formulation	45 mM Tris-HCl, pH 8.0, 124 mM NaCl, 2.4 mM KCl, 18 mM glutathione,10% glycerol.
Species	Human
Application	Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling
Notes	25 mM Tris/HCl, pH 8.0, 137 mM NaCl, 2.7 mM KCl, 1 mM MgCl₂, and 0.1 mg/ml BSA, 20 uM BPS HDAC class 2a substrate (Catalog #50040), and HDAC4. Incubation condition: 30 min at 37°C, followed by HDAC developer (Catalog #50030) for 15 min at room temperature. Fluorescence intensity is measured at ex360/em460. Avoid freeze/thaw cycles.
GenBank	NM_006037
Mw(kda)	76 kDa

Synonyms	histone deacetylase 4, HDAC-4
Uniprot	P56524

Shipping Temperature	-80°C (dry ice)
Format	Aqueous buffer solution
Storage	At least 6 months at -80°C.

Reference	1. Leong, H. et al. (2005) Mol. Endocrinol. 19, 2930-2942.2. Zhao et al., (2005) Mol. Cell. Biol. 25, 8456-8464.3. Wang, C., et al. J Med Chem. 2014 Oct 9;57(19):7999-8009. doi: 10.1021/jm500872p. In Vivo Imaging of Histone Deacetylases (HDACs) in the Central Nervous System and Major Peripheral Organs (2014)

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP18200304	50004	10 ug	$506		Add to Cart

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