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HDAC1, FLAG-tag, His-tag

BHP18200321
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+1 866.986.9598
Email
[email protected]
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Synonyms histone deacetylase 1, HDAC-1
Uniprot Q13547
Shipping Temperature -80°C (dry ice)
Format Aqueous buffer solution
Storage At least 6 months at -80°C.
Reference 1. Rikimaru,T. et al., Oncology 72 (1-2), 69-74 (2007).
2. Ishihama, K. et al., J Clin Pathol 60(11), 1205-10 (2007).Application References:
1. Identification of histone deacetylase inhibitors with benzoylhydrazide scaffold that selectively inhibit class I histone deacetylases (2015)
2. A chimeric SERM-histone deacetylase inhibitor approach to breast cancer therapy (2014)
3. CBP and p300 acetylate PCNA to link its degradation with nucleotide excision repair synthesis (2014)
4. Design, synthesis and evaluation of novel HDAC inhibitors as potential antitumor agents (2014)
5. Design, synthesis, 3D pharmacophore, QSAR, and docking studies of carboxylic acid derivatives as Histone Deacetylase inhibitors and cytotoxic agents (2014)
6.Discovery of a small molecule agonist of phosphatidylinositol 3-kinase p110alpha that reactivates latent HIV-1 (2014)
7. Wang, C., et al. J Med Chem. 2014 Oct 9;57(19):7999-8009. doi: 10.1021/jm500872p. In Vivo Imaging of Histone Deacetylases (HDACs) in the Central Nervous System and Major Peripheral Organs (2014)
8. Meyners, C., et al. Anal Biochem. 2014 Sep 1;460:39-46. doi: 10.1016/j.ab.2014.05.014. Kinetic method for the large-scale analysis of the binding mechanism of histone deacetylase inhibitors (2014)
9.Selective HDAC Inhibition for the Disruption of Latent HIV-1 Infection (2014)
10.The effect of various zinc binding groups on inhibition of histone deacetylases 1-11 (2014)
11. Meyners, C., et al. Mol Recognit. 2014 Mar;27(3):160-72. Thermodynamics of ligand binding to histone deacetylase like amidohydrolase from Bordetella/Alcaligenes (2014)
12.A selective HDAC 1/2 inhibitor modulates chromatin and gene expression in brain and alters mouse behavior in two mood-related tests (2013)
13.Class I HDAC imaging using ( (3)H)CI-994 autoradiography (2013)
14. Fass, D.M., et al. Neuropharmacology. 2013 Jan; 64: 81–96. Crebinostat: a novel cognitive enhancer that inhibits histone deacetylase activity and modulates chromatin-mediated neuroplasticity (2013)
15.FDG-PET imaging reveals local brain glucose utilization is altered by class I histone deacetylase inhibitors (2013)
16.Baud, MGJ, et al. ChemMedChem. 2013 Jan;8(1):149-56. doi: 10.1002/cmdc.201200450. Highly ligand efficient and selective N-2-(Thioethyl)picolinamide histone deacetylase inhibitors inspired by the natural product psammaplin A (2013)
17.Imaging epigenetic regulation by histone deacetylases in the brain using PET/MRI with ¹¸F-FAHA (2013)
18. Marek, M., et al. PLoS Pathog. 2013;9(9):e1003645. doi: 10.1371/journal.ppat.1003645. Structural basis for the inhibition of histone deacetylase 8 (HDAC8), a key epigenetic player in the blood fluke Schistosoma mansoni (2013)
19. Baud, MGJ, et al. Beilstein J Org Chem. 2013;9:81-8. doi: 10.3762/bjoc.9.11. Thioester derivatives of the natural product psammaplin A as potent histone deacetylase inhibitors (2013)
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BHP18200321 50051 50 ug $533.50
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