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Home / Proteins & Peptide

GRO-beta/CINC-3/CXCL2, Rat

SKU : BHP18500420

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Mfr.No.	IX03279, IX03279-1, IX03279-25, IX03279-5
Description	Chemokine (C-X-C motif) ligand 2(CXCL2) is a small cytokine belonging to the CXC chemokine family that is also called macrophage inflammatory protein 2-alpha (MIP2-alpha), Growth-regulated protein beta (Gro-beta) and Gro oncogene-2 (Gro-2). CXCL2 shares 90% amino acid sequence with CXCL1/GROalpha. The GRO proteins are chemotactic for neutrophils and basophils and can activate them through their CXCR1 or CXCR2 receptors.Recombinant Rat GRO-beta/CINC-3/CXCL2 produced in E.coli is a single non-glycosylated polypeptide chain containing 69 amino acids. A fully biologically active molecule, rrGRO-beta has a molecular mass of 7.6kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques.
Reconstitution	Reconstituted in ddH2O or PBS at 100 ug/ml.
Formulation	Lyophilized after extensive dialysis against PBS.
Molecular Weight	7.6 kDa, observed by reducing SDS-PAGE.
Source	E. coli
Endotoxin Level	0.2 EU/ug, determined by LAL method.
Notes	For research use only
Bioactivity	The EC50 value of Rat GRO-beta/CINC-3/CXCL2 on Ca2+ mobilization assay in CHO-K1/Galpha15/rCXCR2 cells (human Galpha15 and rat CXCR2 stably expressed in CHO-K1 cells) is less than 10 ng/ml.

Synonyms	Growth Regulated Protein/Melanoma Growth Stimulatory Activity (MGSA?), CXCL2, MIP-2, GRO2,CINC-3
Sequence	Ser32-Asn100 (Accession #:P30348)

Purity	95% as analyzed by SDS-PAGE.
Storage	Lyophilized recombinant Rat GRO-beta/CINC-3/CXCL2 remains stable up to 6 months at lower than -70°C from date of receipt. Upon reconstitution, Rat GRO-beta/CINC-3/CXCL2 should be stable up to 1 week at 4°C or up to 3 months at -20°C.

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHP18500420-1	IX03279-1	1mg	$2933		Add to Cart
BHP18500420-2	IX03279-25	25ug	$112		Add to Cart
BHP18500420-3	IX03279-5	5ug	$50		Add to Cart

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