Secreted frizzled receptor (FZD4)-Fc fusionprotein and WNT receptor, also known asFZD4, GenBank Accession No.BC_114527, a.a. 37-180, expressed in aHEK293 cell expression system. MW = 42.9kDa (monomer). This protein runs at ahigher apparent M.W. by SDS-PAGE due toglycosylation.
Immunogen Region
37-180
Tag
C-terminal Fc fusion (Human IgG1)
Formulation
Sterile-filtered (0.2 um) solution of 40 mM Tris, pH 8.0, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol.
Species
Human
Application
Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling
Notes
Avoid freeze/thaw cycles.
GenBank
BC_114527
Mw(kda)
42.9 kDa
Synonyms
FZD4
Uniprot
Q9ULV1
Shipping Temperature
-80°C (dry ice)
Format
Aqueous buffer solution
Storage
At least 6 months at -80°C.
Reference
1. Moffat LL., et al., Development. 2014 Feb;141(3):617-28. 2. Surana, R., et al., Biochim Biophys Acta. 2014 Jan;1845(1):53-65.