Human FGFR2, also known as Fibroblast growth factor receptor 2, Keratinocyte growth factor receptor, BBDS, BEK, BFR-1 and CD332, GenBank Accession No. NM_000141, a.a. 400-821(end), with deletion at 429-430, with C-terminal His-tag, expressed in an Sf9 infected baculovirus expression system. MW = 52 kDa. This protein was isolated from a co-expression with PTP1B. Percentage of phosphorylation<= 10%.
Specific activity: 160 pmole/min/ug
Immunogen Region
400- 821(end), with deletion at 429-430
Tag
C-terminal His-tag
Formulation
40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 0.04% Tween-20, 100 mM Imidazole, 3 mM DTT and 20% glycerol.
Species
Human
Application
Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Notes
Assay was done according to BPS Catalog#79502 with a FGFR2 titration range of 0 ng/rxn-500 ng/rxn.