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Home / Proteins & Peptide

FGF-basic (146aa), Human

SKU : BHP18500327

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Mfr.No.	IX03166, IX03166-1, IX03166-10, IX03166-50
Description	Fibroblast Growth Factor-basic (FGF-basic), also known as FGF-2, is a pleiotropic cytokine and one of the prototypic members of the heparin-binding FGF family. Like other FGF family members, FGF-basic has the beta trefoil structure. In vivo, FGF-basic is produced by a variety of cells, including cardiomycotes, fibroblasts, and vascular cells. FGF-basic regulates a variety of processes including cell proliferation, differentiation, survival, adhesion, motility, apoptosis, limb formation and wound healing. FGF-basic can be tumorigenic due to its role in angiogenesis and blood vessel remodeling. The angiogenic effects of FGF-basic can produce beneficial cardioprotection during acute heart injury.Recombinant human Fibroblast Growth Factor-basic (146 a.a.) (rhFGF-basic) produced in E. coli is a single non-glycosylated polypeptide chain containing 146 amino acids. A fully biologically active molecule, rhFGF-basic has a molecular mass of 16.4 kDa analyzed by reducing SDS-PAGE and is obtained by proprietary chromatographic techniques.
Reconstitution	Reconstituted in ddH2O at 50 ug/mL.
Formulation	Lyophilized after extensive dialysis against PBS.
Molecular Weight	16.4 kDa, observed by reducing SDS-PAGE.
Source	E. coli
Host	Human
Accession Number	P09038
Endotoxin Level	0.2 EU/ug, determined by LAL method.
Notes	For research use only
Bioactivity	ED50 0.25 ng/mL, measured by the cell proliferation assay using 3T3 cells, corresponding to a specific activity of 4 x 106 units/mg.

Synonyms	FGF-2; BFGF; FGFB; HBGF-2
Sequence	PALPEDGGSG AFPPGHFKDP KRLYCKNGGF FLRIHPDGRVDGVREKSDPH IKLQLQAEER GVVSIKGVCA NRYLAMKEDGRLLASKCVTD ECFFFERLES NNYNTYRSRK YTSWYVALKRTGQYKLGSKT GPGQKAILFL PMSAKS

Purity	95% by SDS-PAGE analysis.
Storage	Lyophilized recombinant human Fibroblast Growth Factor-basic (146 a.a.) (rhFGF-basic) remains stable up to 6 months at lower than -70°C from date of receipt. Upon reconstitution, rhFGF-basic remains stable up to 2 weeks at 4°C or up to 3 months at -20°C.

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHP18500327-1	IX03166-1	1mg	$749		Add to Cart
BHP18500327-2	IX03166-10	10ug	$49		Add to Cart
BHP18500327-3	IX03166-50	50ug	$107		Add to Cart

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