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Home / Proteins & Peptide

FGF-4, Human

SKU : BHP18500190

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Mfr.No.	IX02984, IX02984-100, IX02984-25, IX02984-5
Description	Fibroblast Growth Factor-4 (FGF-4) also known as K-FGF is a heparin-binding growth factor of the FGF family.It was identified by its oncogenic transforming activity. FGF-4 and FGF-3 are located closely on chromosome 11. FGF-4 and its receptors (FGF R1c, 2c, 3c and 4) play an important role in the regulation of embryonic development, cell proliferation, and cell differentiation. FGF-4 is required for normal limb and cardiac valve development during embryogenesis.Recombinant human Fibroblast Growth Factor-4 (rhFGF-4) produced in E. coli is a single non-glycosylated polypeptide chain containing 177 amino acids. A fully biologically active molecule obtained by proprietary chromatographic techniques, rhFGF-4 has a molecular mass of 19.4kDa as analyzed by reducing SDS-PAGE.
Reconstitution	Reconstituted in ddH2O at 100 ug/ml.
Formulation	Lyophilized after extensive dialysis against 50mM HEPES, 750mM NaCl, pH7.5.
Molecular Weight	19.4kDa, observed by reducing SDS-PAGE.
Source	E. coli
Host	Human
Endotoxin Level	0.2 EU/ug, determined by LAL method.
Notes	For research use only
Bioactivity	ED500.5ng/ml, measured in a cell proliferation assay using 3T3 cells, corresponding to a specific activity of 2.0x 106 units/mg.

Synonyms	HBGF-4; HST; HST-1; HSTF1; K-FGF; KFGF.
Sequence	MAPTAPNGTL EAELERRWES LVALSLARLP VAAQPKEAAVQSGAGDYLLG IKRLRRLYCN VGIGFHLQAL PDGRIGGAHADTRDSLLELS PVERGVVSIF GVASRFFVAM SSKGKLYGSPFFTDECTFKE ILLPNNYNAY ESYKYPGMFI ALSKNGKTKKGNRVSPTMKV THFLPRL

Purity	95% by SDS-PAGE and HPLC analyses.
Storage	Lyophilized recombinant human Fibroblast Growth Factor-4 (rhFGF-4) remains stable up to 6 months at lower than -70°C from date of receipt. Upon reconstitution, rhFGF-4 should be stable up to 2 weeks at 4°C or up to 3 months at -20°C.

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHP18500190-1	IX02984-100	100ug	$312		Add to Cart
BHP18500190-2	IX02984-25	25ug	$107		Add to Cart
BHP18500190-3	IX02984-5	5ug	$50		Add to Cart

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