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Home / Proteins & Peptide

FGF-10, Mouse

SKU : BHP18500316

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iXCells Biotechnologies

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Mfr.No.	IX03155, IX03155-1, IX03155-10, IX03155-50
Description	Fibroblast Growth Factor-10 (FGF-10) is a mitogen mainly produced by mesenchymal stem cells in lung. FGF-10 belongs to the heparin binding FGF family, and is also known as Keratinocyte Growth Factor-2 (KGF-2). It shares homology with KGF, and both KGF and FGF-10 activate the receptor FGFR2-IIIb. However, unlike KGF, which induces the proliferation and differentiation of various epithelial cells, FGF-10 is an essential factor for the budding and branching morphogenesis during multi-organ development via mesenchymal-epithelial interactions. FGF-10 is crucial for lung and limb development and is regulated by Shh during early development. Recombinant mouse Fibroblast Growth Factor-10 (rmFGF-10) produced in E. coli is a single non-glycosylated polypeptide chain containing 148 amino acids. A fully biologically active molecule, rmFGF-10 has a molecular mass of 17.0 kDa analyzed by reducing SDS-PAGE and is obtained by proprietary chromatographic techniques.
Reconstitution	Reconstituted in ddH2O at 100 ug/mL.
Formulation	Lyophilized after extensive dialysis against PBS.
Molecular Weight	17.0 kDa, observed by reducing SDS-PAGE.
Source	E. coli
Host	Mouse
Accession Number	O35565
Endotoxin Level	0.2 EU/ug, determined by LAL method.
Notes	For research use only
Bioactivity	ED50 10 ng/mL, measured by a cell proliferation assay using 4MBr-5 cells, corresponding to a specific activity of 1.0x 105 units/mg.

Synonyms	Fibroblast Growth Factor-10, FGFA, Keratinocyte growth factor-2
Sequence	SSAGRHVRSY NHLQGDVRWR RLFSFTKYFL TIEKNGKVSGTKNEDCPYSV LEITSVEIGV VAVKAINSNY YLAMNKKGKLYGSKEFNNDC KLKERIEENG YNTYASFNWQ HNGRQMYVALNGKGAPRRGQ KTRRKNTSAH FLPMTIQT

Purity	95% as analyzed by SDS-PAGE and HPLC.
Storage	Lyophilized recombinant mouse Fibroblast Growth Factor-10 (rmFGF-10) remains stable up to 6 months at lower than -70°C from date of receipt. Upon reconstitution, rmFGF-10 remains stable up to 2 weeks at 4°C or up to 3 months at -20°C.

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHP18500316-1	IX03155-1	1mg	$1872		Add to Cart
BHP18500316-2	IX03155-10	10ug	$82		Add to Cart
BHP18500316-3	IX03155-50	50ug	$199		Add to Cart

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