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Home / Proteins & Peptide

FAP, His-tag

SKU : BHP18200788

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BPS Bioscience

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Mfr.No.	80100
Description	Human FAP (GenBank Accession No. NM_004460), (a.a. 29-end) with C-terminal His-tag, MW=85.5 kDa, expressed in a Baculovirus infected Sf9 cell expression system. Specific activity: >= 83 pmol/min/ug.
Background	Fibroblast Activation Protein, or FAP, is a 170 kDa dimer withdipeptidase activity. FAP expression is seen on activated stromal fibroblasts in>90% ofall human carcinomas, suggesting a role in the development, growth and metastasis ofcarcinomas. It is also involved in the control of wound healing and tissue repair.
Immunogen Region	29-end
Tag	C-terminal His-tag
Formulation	40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 200 mM imidazole, and 20% glycerol.
Species	Human
Application	Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling
Notes	50 mM Tris-HCl (pH 7.5),10 mM MgCl₂, 1 mM MnCl₂, 5 uMsubstrate (A-P-AMC), incubation 10 min atroom temperature. Avoid freeze/thaw cycles.
GenBank	NM_004460
Mw(kda)	85.5 kDa

Synonyms	Fibroblast Activation Protein, seprase
Uniprot	Q12884

Shipping Temperature	-80°C (dry ice)
Format	Aqueous buffer solution
Storage	At least 6 months at -80°C.

Reference	1. Edosada,C.Y. et al., J. Biol. Chem. 281 (11), 7437-7444 (2006). 2. Edosada,C.Y. et al., FEBS Lett. 580 (6), 1581-1586 (2006).

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SKU	Supplier No.	Size	Your price	Quantity
BHP18200788	80100	25 ug	$533.50		Add to Cart

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