Mouse FAP, GenBank Accession No. NM_007986, amino acids 26-762 (end), with C-terminal His-tag, MW=88 kDa, expressed in HEK293 expression system.
Background
FAP expression is seen on activated stromal fibroblasts in>90% ofall human carcinomas, suggesting a role in the development, growth and metastasis ofcarcinomas. It is also involved in the control of wound healing and tissue repair.
Immunogen Region
26-762 (end)
Tag
C-terminal His-tag
Formulation
8 mM phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol.
Species
Mouse
Notes
Avoid freeze/thaw cycles.
GenBank
NM_007986
Mw(kda)
88 kDa
Synonyms
Fibroblast Activation Protein, seprase
Uniprot
Q12884
Shipping Temperature
-80°C (dry ice)
Format
Aqueous buffer solution
Storage
At least 6 months at -80°C.
Reference
1. Edosada,C.Y. et al., J. Biol. Chem. 281 (11), 7437-7444 (2006). 2. Edosada,C.Y. et al., FEBS Lett. 580 (6), 1581-1586 (2006).