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Home / Proteins & Peptide

Exodus-2/CCL21, Human

SKU : BHP18500096

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iXCells Biotechnologies

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Mfr.No.	IX02843, IX02843-1, IX02843-20
Description	Exodus-2/CCL21 is a novel CC chemokine discovered independently by three groups from the EST database, and shows 21-33% identity to other CC chemokines. Exodus-2 contains the four conserved cysteines characteristic of ß chemokines plus two additional cysteines in its unusually long carboxylterminal domain. It is expressed in lymph nodes of certain endothelial cells, and in the spleen and appendix. Exodus-2 chemoattracts T and B lymphocytes and inhibits hematopoiesis.
Reconstitution	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at <= -20 °C. Further dilutions should be made in appropriate buffered solutions.
Formulation	Lyophilized from a 0.2 um filtered concentrated solution in 20 mM PB, pH 7.4, 150 mM NaCl.
Molecular Weight	Approximately 12.2 kDa, a single, non-glycosylated polypeptide chain containing 111 amino acids.
Physical Appearance	Sterile Filtered White lyophilized (freeze-dried) powder.
Source	E. coli
Host	Human
Usage	This material is for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE.'
Endotoxin Level	Less than 1 EU/ug of rHuExodus-2/CCL21 as determined by LAL method.
Bioactivity	Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human lymphocytes is in a concentration range of 10-100 ng/ml.

Synonyms	Exodus-2/CCL21, Human;
Sequence	SDGGAQDCCL KYSQRKIPAK VVRSYRKQEP SLGCSIPAILFLPRKRSQAE LCADPKELWV?QQLMQHLDKT PSPQKPAQGC RKDRGASKTGKKGKGSKGCK RTERSQTPKG P

Purity	97 % by SDS-PAGE and HPLC analyses.
Storage	This lyophilized preparation is stable at 2-8 °C, but should be kept at -20 °C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 °C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 °C to -70 °C. Avoid repeated freeze/thaw cycles.

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHP18500096-1	IX02843-1	1mg	$2621		Add to Cart
BHP18500096-2	IX02843-20	20ug	$199		Add to Cart

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