JavaScript is currently not supported/disabled by this browser. Please enable JavaScript for full functionality.

Call Us 1 - 866 - 986 - 9598
[email protected]

Sign Up

Login
- My Order
- Return Requests
- Track my Order

Home / Proteins & Peptide

ELOB/ELOC/VHL Complex

SKU : BHP18201149

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Request More Infos

BPS Bioscience

view supplier details

Order Now

Credit card payments now incur a 3% fee.

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Ask Merchant

Request More Infos

Sample Request

Mfr.No.	100361-2
Description	ELOB/ELOC/VHL complex of human ELOB (GenBank Accession No. NM_007108), a.a. 2-118 with N-terminal FLAG-tag and MW= 14 kDa; ELOC (GenBank Accession No. NM_005648), a.a. 2-86 with N-terminal His-tag and MW= 13; human VHL (GenBank Accession No. NM_000551) a.a. 2-212(end) with N-terminal FLAG-tag and MW= 25 kDa, individually expressed in a HEK293 expression system.
Immunogen Region	VHL: 2-212(end); ELOB: 2-118; ELOC: 2-112(end)
Tag	VHL: N-terminal FLAG-tag; ELOB: N-terminal FLAG-tag; ELOC: N-terminal His-tag
Formulation	40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 20% glycerol, 3 mM DTT.
Species	Human
Application	Useful for the study of protein degradation and PROTAC design, and selectivity profiling.
Notes	ARV-771-mediated binding of VHL BPS #100361 to BET bromodomain was assessed using A-screen technology. Various amounts of VHL were incubated in 10-ul reaction with ARV-771 and GST-BRD3(BD2) BPS #31033 at room temperature for one hour. After this, FLAG-acceptor beads and GSH-donor beads were added followed by detection of A-counts. Avoid freeze/thaw cycles.
GenBank	VHL: NM_000551; ELOB: NM_007108; ELOC: NM_005648
Mw(kda)	VHL: 25 kDa; ELOB: 14 kDa; ELOC: 13 kDa

Synonyms	VHL, ELOB, ELOC,
Uniprot	VHL: P40337; ELOB: Q15370; ELOC: Q15369

Shipping Temperature	-80°C (dry ice)
Format	Aqueous buffer solution
Storage	At least 6 months at -80°C.

Reference	1. Kamura, T., et al., Science. 1999; 284(5414): 657-661. 2. Stebbins, C.E., et al., Science. 1999; 284(5413): 455-461.

Product Manual	Datasheet

Have you used this product?

Rate it now..!!

Login to Review

SKU	Supplier No.	Size	Your price	Quantity
BHP18201149	100361-2	50 ug	$588.50		Add to Cart

ebiohippo.com provides biomedical researchers with a one-stop informatic shopping experience by transforming biotechnology products’ data into a ready-to-analyze state. We collect and unify suppliers’ data on a single platform to reduce the time of searching, uncertainty, and cost of scientific experiments.

© 2024 Biohippo. All rights reserved.