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Home / Proteins & Peptide

EGF, Mouse

SKU : BHP18500180

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iXCells Biotechnologies

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Mfr.No.	IX02972, IX02972-1, IX02972-10, IX02972-50
Description	Epidermal Growth Factor (EGF) was originally discovered in crude preparations of nerve growth factor prepared from mouse submaxillary glands as an activity that induced early eyelid opening, incisor eruption, hair growth inhibition, and stunting of growth when injected into newborn mice. EGF is a potent growth factor that stimulates the proliferation of various epidermal and epithelial cells. Additionally, EGF has been shown to inhibit gastric secretion, and to be involved in wound healing. EGF signals through a receptor known as c-erbB, which is a class I tyrosine kinase receptor. This receptor also binds with TGF-alpha and VGF (vaccinia virus growth factor).Recombinant mouse Epidermal Growth Factor (rmEGF) produced in E. coli is a single non-glycosylated polypeptide chain containing 54 amino acids. A fully biologically active molecule, rmEGF is obtained by proprietary chromatographic techniques with a molecular mass of 6.2kDa analyzed by reducing SDS-PAGE.
Reconstitution	Reconstituted in ddH2O at 100 ug/ml.
Formulation	Lyophilized after extensive dialysis against PBS.
Molecular Weight	6.2 kDa, observed by reducing SDS-PAGE.
Source	E. coli
Host	Mouse
Endotoxin Level	0.2 EU/ug, determined by LAL method.
Notes	For research use only
Bioactivity	ED50 0.1ng/ml, measured by a cell proliferation assay using BALB/c 3T3 cells, corresponding to a specific activity of 1.0x 107units/mg.

Synonyms	Epidermal Growth Factor, Urogastrone, URG
Sequence	MNSYPGCPSS YDGYCLNGGV CMHIESLDSY TCNCVIGYSGDRCQTRDLRW WELR

Purity	95% by SDS-PAGE and HPLC analysis.
Storage	Lyophilized recombinant mouse Epidermal Growth Factor (rmEGF) remains stable up to 6 months at lower than -70°C from date of receipt. Upon reconstitution, rmEGF should be stable up to 2 weeks at 4°C or up to 3 months at -20°C.

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHP18500180-1	IX02972-1	1mg	$157		Add to Cart
BHP18500180-2	IX02972-10	10ug	$20		Add to Cart
BHP18500180-3	IX02972-50	50ug	$32		Add to Cart

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