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Home / Proteins & Peptide

DPY30, His-tag

SKU : BHP18200636

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Mfr.No.	71203
Description	Human dpy-30 homolog, or DPY30, GenBank Accession No. NM_032574, a.a. 2 - 99 (end) with N-terminal His-tag, MW= 12 kDa, expressed in an E. coli expression system.
Background	As part of the MLL1/MLL complex, involved in the methylation of histone H3 at Lys-4, particularly trimethylation. Histone H3 Lys-4 methylation represents a specific tag for epigenetic transcriptional activation. May play some role in histone H3 acetylation. In a teratocarcinoma cell, plays a crucial role in retinoic acid-induced differentiation along the neural lineage, regulating gene induction and H3 Lys-4 methylation at key developmental loci. May also play an indirect or direct role in endosomal transport.
Immunogen Region	2-99 (end)
Tag	N-terminal His-tag
Formulation	45 mM Tris-HCl pH 8.0, 124 mM NaCl, 2.4 mM KCl, 225 mM Imidazole, 1 mM TCEP, 1 uM ZnCl2, 10% Glycerol
Species	Human
Application	Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling
Notes	Avoid freeze/thaw cycles.
GenBank	NM_032574
Mw(kda)	12 kDa

Synonyms	DPY30, HDPY30
Uniprot	Q9C005

Shipping Temperature	-80°C (dry ice)
Format	Aqueous buffer solution
Storage	At least 6 months at -80°C.

Reference	1. Xu, Z., et al., J Cell Biol. 2009 Aug 10 ; 186(3) : 343-53 2. Patel, A., et al., J Biol Chem. 2009 Sep 4 ; 284(36) : 24242-56

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP18200636	71203	50 ug	$495		Add to Cart

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