Human DPP7 (GenBank Accession No. NM_013379), a.a. 26-end with C-terminal His-tag, MW=52.5 kDa, expressed in a Baculovirus infected Sf9 cell expression system.
Specific activity: >= 1880 pmol/min/ug.
Background
Dipeptidyl peptidase-7 (DPP7), also known as DPP2, is a serineaminopeptidase found in quiescent lymphocytes. Inhibition of this enzyme inducesapoptosis, and levels of DPP7 are elevated in many tumors, suggesting that DPP7 may beinvolved in a novel pathway for tumor suppression.
Immunogen Region
26-end
Tag
C-terminal His-tag
Formulation
40 mM Tris-HCl, pH 8.0,110 mM NaCl, 2.2 mM KCl, 220 mM imidazole, and 20% glycerol
Species
Human
Application
Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling
Notes
10 mM Tris-HCl, pH 7.4,10 mM MgCl2, 1 mM MnCl2, 20 uM Ala-Pro-AMC,10 min, room temperature.