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Home / Proteins & Peptide

DPP4, His-tag

SKU : BHP18200784

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BPS Bioscience

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Mfr.No.	80040
Description	Human DPP4 (GenBank Accession No. NM_001935), a.a. 29-end with C-terminal His-tag, MW=89.1 kDa, expressed in a Baculovirus infected Sf9 cell expression system. Specific activity: >= 4630 pmole/min/ug
Background	Dipeptidyl peptidase-4 (DPP4), also known as adenosine deaminasecomplexing protein 2, is a serine exopeptidase that cleaves X-proline dipeptides from theN-terminus of polypeptides. DPP4 plays a key role in glucose metabolism, immuneregulation, signal transduction and apoptosis.
Immunogen Region	29-end
Tag	C-terminal His-tag
Formulation	45 mM Tris-HCl, pH 8.0,124 mM NaCl, 2.4 mM KCl, 225 mM imidazole,10% glycerol and 3 mM DTT.
Species	Human
Application	Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling
Notes	50 mM Tris (pH 7.5), 0.1%BSA, 20 uM substrate (A-P-AMC), room temperature for 10 min. Avoid freeze/thaw cycles.
GenBank	NM_001935
Mw(kda)	89.1 kDa

Synonyms	DPPIV, CD26, Dipeptidylpeptidase 4, ADCP2
Uniprot	P27487

Shipping Temperature	-80°C (dry ice)
Format	Aqueous buffer solution
Storage	At least 6 months at -80°C.

Reference	1. Deacon CF, Carr RD, and Holst JJ Front Biosci. 2008 Jan 1;13:1780-94. 2. Langley AK, Suffoletta TJ, and Jennings HRPharmacotherapy. 2007 Aug;27(8):1163-80.Application Reference:Ravassa, S., et al. Cardiovasc Diabetol. 2013 Oct 7;12:143. doi: 10.1186/1475-2840-12-143. The activity of circulating dipeptidyl peptidase-4 is associated with subclinical left ventricular dysfunction in patients with type 2 diabetes mellitus (2013)

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SKU	Supplier No.	Size	Your price	Quantity
BHP18200784	80040	10 ug	$528		Add to Cart

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